The Neuroplastin Polyclonal Antibody (CAB7972) is a vital tool for researchers studying neuroplastin, a cell adhesion molecule with key roles in brain development and synaptic plasticity. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it suitable for use in a variety of applications, including Western blotting.Neuroplastin, also known as Np65, is involved in promoting neuronal growth, synaptic connectivity, and learning and memory processes. Dysregulation of neuroplastin has been linked to neurodevelopmental disorders, cognitive impairments, and neurodegenerative diseases.
Therefore, the ability to detect and analyze neuroplastin expression in different cell types is crucial for understanding its functional significance in various physiological and pathological conditions.By utilizing the Neuroplastin Polyclonal Antibody, researchers can gain valuable insights into the molecular mechanisms underlying neuronal plasticity and cognitive function. This antibody provides a reliable tool for investigating the role of neuroplastin in neurological disorders and exploring potential therapeutic strategies targeting this protein.
Product Name:
NPTN Rabbit Polyclonal Antibody
SKU:
CAB7972
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-200 of human NPTN (NP_059429.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
44kDa
Observed MW:
45kDa
This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27020
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NPTN antibody (CAB7972) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
