The NPSR1 Polyclonal Antibody (CAB16619) is a valuable tool for researchers studying NPSR1, a G protein-coupled receptor that plays a role in the regulation of immune responses and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the NPSR1 protein, this antibody enables the detection and analysis of NPSR1 expression in a variety of cell types, making it suitable for research in immunology and inflammatory diseases.
NPSR1, also known as the neuropeptide S receptor, is involved in the modulation of immune responses and inflammation, making it a potential target for therapeutic interventions in conditions such as asthma, allergic diseases, and chronic inflammatory disorders. Understanding the role of NPSR1 in immune regulation is crucial for the development of targeted therapies that can modulate immune responses and alleviate inflammation in these pathological conditions.
Product Name:
NPSR1 Rabbit Polyclonal Antibody
SKU:
CAB16619
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human NPSR1 (NP_001287863.1).
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
387129
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NPSR1 Rabbit pAb (CAB16619) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
