The NPRL2 Polyclonal Antibody (CAB16486) is a valuable tool for researchers studying the NPRL2 protein, a key component of the GATOR1 complex involved in the regulation of mTORC1 signaling pathway. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.NPRL2 plays a crucial role in cellular growth and metabolism by regulating mTORC1 activity, making it a target of interest in cancer research and metabolic disorders. The NPRL2 Polyclonal Antibody binds specifically to NPRL2 protein, enabling researchers to detect and analyze its expression in various cell types.
By understanding the function of NPRL2, researchers can gain insights into the mechanisms underlying cell growth and metabolism, offering potential therapeutic targets for diseases like cancer and metabolic disorders. The NPRL2 Polyclonal Antibody is a valuable tool for investigating the role of NPRL2 in these contexts and advancing our understanding of cellular signaling pathways.
Product Name:
NPRL2 Rabbit Polyclonal Antibody
SKU:
CAB16486
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NPRL2 (NP_006536.3).
Enables protein kinase activity. Contributes to GTPase activator activity. Involved in cellular response to amino acid starvation; negative regulation of TOR signaling; and negative regulation of kinase activity. Located in lysosomal membrane. Part of GATOR1 complex. Implicated in focal epilepsy.
Purification Method:
Affinity purification
Gene ID:
10641
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NPRL2 Rabbit pAb (CAB16486) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
