ANPRB/NRP2 Rabbit Polyclonal Antibody (CAB16061)
- SKU:
- CAB16061
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ANPRB/NRP2 Rabbit Polyclonal Antibody |
SKU: | CAB16061 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-320 of human ANPRB/NRP2 (NP_003986.2). |
Sequence: | SAKN DHYR TLVR TGPS APKL GEFV VTLH GHFN WTAR AALL YLDA RTDD RPHY FTIE GVFE ALQG SNLS VQHQ VYAR EPGG PEQA THFI RANG RIVY ICGP LEML HEIL LQAQ RENL TNGD YVFF YLDV FGES LRAG PTRA TGRP WQDN RTRE QAQA LREA FQTV LVIT YREP PNPE YQEF QNRL LIRA RED |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GCB; AMD1; AMDM; ANPb; ECDM; GC-B; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B; ANPRB/NRP2 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein |
Calculated MW: | 117kDa |
Observed MW: | 117kDa |
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
Purification Method: | Affinity purification |
Gene ID: | 4882 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |