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NPPA Polyclonal Antibody

SKU:
CAB23268
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

NPPA Polyclonal Antibody (CAB23268)

The NPPA Polyclonal Antibody is a crucial tool for researchers studying Natriuretic Peptide A (NPPA), a hormone involved in regulating blood pressure and cardiovascular function. This antibody, developed using rabbit immunization, is highly specific for human NPPA and has been validated for use in various applications, including Western blotting.NPPA, also known as atrial natriuretic peptide, is a key player in the body's regulation of fluid balance, blood pressure, and overall cardiovascular health. Dysregulation of NPPA expression has been linked to conditions such as hypertension, heart failure, and kidney disease, making it a promising target for therapeutic intervention.

By using the NPPA Polyclonal Antibody, researchers can accurately detect and quantify NPPA levels in various biological samples, allowing for a better understanding of the hormone's role in health and disease. This antibody is an essential tool for studies in cardiology, endocrinology, and molecular biology, offering valuable insights into the mechanisms underlying cardiovascular disorders.

Product Name:NPPA Polyclonal Antibody
Product Code:CAB23268
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples:Mouse heart, Rat heart

This gene encodes members of the natriuretic family of peptides that play an important role in the control of extracellular fluid volume and electrolyte homeostasis. The encoded protein precursor undergoes proteolytic processing to generate multiple functional peptides. Mice lacking the encoded peptides exhibit salt-sensitive hypertension. The transgenic overexpression of the encoded peptides in mice decreases arterial blood pressure without inducing diuresis and natriuresis. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 4.

Immunogen:Recombinant protein of mouse NPPA.
Sequence:Email for sequence
Synonyms:ANP, Anf, CDD, Pnd
Calculated MW:17kDa
Observed MW:17kDa

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