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NPM1 Monoclonal Antibody [PAT23F1AT] (CPAB0631)

SKU:
CPAB0631
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT23F1AT
Applications:
WB
ELISA
FC
€149
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Description

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NPM1 Monoclonal Antibody [PAT23F1AT] (CPAB0631)

The NPM1 Polyclonal Antibody (CPAB0631) is a crucial tool for researchers studying NPM1, a nucleolar phosphoprotein involved in various cellular processes, including ribosome biogenesis and regulation of cell proliferation. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting NPM1 in human samples, making it a reliable choice for Western blot applications.NPM1 is a multifunctional protein that has been implicated in numerous diseases, including acute myeloid leukemia (AML) where mutations in NPM1 are commonly found.

By targeting NPM1, researchers can gain insights into the role of this protein in cancer development and progression, potentially leading to the identification of novel therapeutic targets.The NPM1 Polyclonal Antibody is a valuable tool for researchers investigating the function of NPM1 in both normal and diseased states. Its high reactivity and specificity make it an essential component of any study aiming to elucidate the molecular mechanisms underlying NPM1-related diseases.

Product Name:NPM1 Antibody
Product Sku:CPAB0631
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NPM1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NPM1 protein 1-294 amino acids purified from Ecoli.
Clone:PAT23F1AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:NPM1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Nucleophosmin (NPM1) is a phosphoprotein which shuffles between the nucleus and the cytoplasm. NPM1 is assumed to be involved in a number of processes including regulation of the ARF/p53 pathway. Several genes fusion partners have been described, particularly the anaplastic lymphoma kinase gene on chromosome 2. NPM1 gene mutations are linked with acute myeloid leukemia.
Synonyms:Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM, B23.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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