The NPLOC4 Polyclonal Antibody (CAB3256) is a valuable tool for researchers studying NPLOC4, a protein involved in DNA repair and cell cycle regulation. This antibody, raised in rabbits, is highly specific for NPLOC4 in human samples and has been validated for use in various applications, including Western blotting.NPLOC4 plays a crucial role in maintaining genomic stability and promoting cell survival under stress conditions. Its functions in DNA damage repair pathways make it a potential target for cancer therapy and research into genetic disorders.
By detecting and analyzing NPLOC4 expression in different cell types, this antibody aids in understanding its role in cellular processes and disease development.Researchers in the fields of oncology, genetics, and cell biology will benefit from using the NPLOC4 Polyclonal Antibody for their studies on DNA repair mechanisms, cell cycle regulation, and potential therapeutic targets for cancer and other genetic diseases. Unlock the mysteries of NPLOC4 with this reliable and specific antibody.
Product Name:
NPLOC4 Rabbit Polyclonal Antibody
SKU:
CAB3256
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NPLOC4 (NP_060391.2).
Predicted to enable ATPase binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to K48-linked polyubiquitin modification-dependent protein binding activity and K63-linked polyubiquitin modification-dependent protein binding activity. Involved in negative regulation of RIG-I signaling pathway; negative regulation of type I interferon production; and proteolysis involved in cellular protein catabolic process. Located in nucleus. Part of UFD1-NPL4 complex and VCP-NPL4-UFD1 AAA ATPase complex.
Purification Method:
Affinity purification
Gene ID:
55666
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NPLOC4 antibody (CAB3256) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
