The NPFF Polyclonal Antibody (CAB7020) is a valuable tool for researchers studying the Neuropeptide FF (NPFF) receptor, a G protein-coupled receptor involved in the regulation of pain, stress responses, and appetite. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples, making it ideal for use in Western blot applications. By binding to the NPFF receptor protein, this antibody allows for the detection and analysis of NPFF receptor expression in various cell types, enabling further investigation into its role in pain perception and other physiological processes.
The NPFF receptor is known to modulate pain sensitivity and is a potential target for the development of novel analgesic drugs. Research into the NPFF receptor's function may provide insights into the pathophysiology of chronic pain conditions and aid in the development of targeted therapies for pain management. By utilizing the NPFF Polyclonal Antibody (CAB7020), researchers can further elucidate the mechanisms underlying NPFF receptor signaling and potentially contribute to the discovery of new therapeutic interventions for pain-related disorders.
Product Name:
NPFF Rabbit Polyclonal Antibody
SKU:
CAB7020
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 34-113 of human NPFF (NP_003708.1).
This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
8620
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat plasma, using NPFF antibody (CAB7020) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5min.
