UniProt Protein Function: | NPBWR2: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCRChromosomal Location of Human Ortholog: 20q13.3Cellular Component: integral to membrane; integral to plasma membrane; neuron projection; plasma membraneMolecular Function: neuropeptide binding; neuropeptide receptor activity; opioid receptor activity; protein bindingBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; synaptic transmission |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008] |
UniProt Code: | P48146 |
NCBI GenInfo Identifier: | 160332190 |
NCBI Gene ID: | 2832 |
NCBI Accession: | P48146.2 |
UniProt Secondary Accession: | P48146,Q6NWQ6, Q9H4K3 |
UniProt Related Accession: | P48146 |
Molecular Weight: | 36,861 Da |
NCBI Full Name: | Neuropeptides B/W receptor type 2 |
NCBI Synonym Full Names: | neuropeptides B/W receptor 2 |
NCBI Official Symbol: | NPBWR2Â Â |
NCBI Official Synonym Symbols: | GPR8Â Â |
NCBI Protein Information: | neuropeptides B/W receptor type 2 |
UniProt Protein Name: | Neuropeptides B/W receptor type 2 |
UniProt Synonym Protein Names: | G-protein coupled receptor 8 |
Protein Family: | |
UniProt Gene Name: | NPBWR2Â Â |
UniProt Entry Name: | NPBW2_HUMAN |