The NPAS1 Polyclonal Antibody (PAC010904) is a vital tool for researchers studying the NPAS1 protein, a transcription factor involved in the regulation of neuronal development and function. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By targeting the NPAS1 protein, this antibody enables the detection and analysis of NPAS1 expression in various cell types, making it an indispensable tool for studies in neuroscience and neurodevelopmental disorders.NPAS1 plays a crucial role in the development and function of neurons, making it a key player in processes such as neuronal differentiation, synaptic plasticity, and neuronal survival.
Research on NPAS1 is essential for understanding brain development, cognitive function, and the pathogenesis of neurological disorders. The NPAS1 Polyclonal Antibody provides researchers with a reliable means to investigate the functions and mechanisms of NPAS1, paving the way for advancements in neurobiology and the development of potential therapies for neurological conditions.
neuronal PAS domain protein 1;NPAS1;MOP5;PASD5;bHLHe11 ;
UniProt Protein Function:
NPAS1: May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 19q13.2-q13.3Cellular Component: nucleusMolecular Function: protein dimerization activity; signal transducer activity; DNA binding; transcription factor activityBiological Process: startle response; central nervous system development; transcription, DNA-dependent; maternal behavior; negative regulation of transcription from RNA polymerase II promoter; signal transduction
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008]
