The NPAS1 Polyclonal Antibody (PACO04458) is a powerful tool for researchers investigating the NPAS1 protein, a transcription factor associated with various biological processes, including neuronal development and circadian rhythm regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting NPAS1 in human samples, making it suitable for use in immunohistochemistry and Western blotting experiments.NPAS1, part of the basic helix-loop-helix-PAS family of transcription factors, is known for its role in neuronal differentiation and function, making it a key target for studies on neurodevelopmental disorders and neurological conditions.
By targeting NPAS1, researchers can gain insights into the molecular mechanisms underlying these diseases, potentially leading to new therapeutic strategies and treatments.The NPAS1 Polyclonal Antibody (PACO04458) offers researchers a reliable tool for investigating the functions and regulation of NPAS1 in various cellular contexts, making it an essential component of studies in neuroscience, neurology, and related fields. Its high specificity and sensitivity ensure accurate and reproducible results, aiding in the advancement of scientific knowledge and the development of potential therapies for NPAS1-related disorders.
Antibody Name:
NPAS1 Antibody
Antibody SKU:
PACO04458
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Neuronal PAS1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NPAS1; BHLHE11; MOP5; PASD5; Neuronal PAS domain-containing protein 1; Neuronal PAS1; Basic-helix-loop-helix-PAS protein MOP5; Class E basic helix-loop-helix protein 11; bHLHe11; Member of PAS protein 5; PAS domain-containing protein 5
UniProt Protein Function:
NPAS1: May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 19q13.2-q13.3Cellular Component: nucleusMolecular Function: protein dimerization activity; signal transducer activity; DNA binding; transcription factor activityBiological Process: startle response; central nervous system development; transcription, DNA-dependent; maternal behavior; negative regulation of transcription from RNA polymerase II promoter; signal transduction
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008]
