The NPAP1 Antibody (PAC019223) is a valuable tool for researchers studying NPAP1, a protein associated with neuronal function and neurodegenerative disorders. This polyclonal antibody, produced using advanced technology, exhibits high specificity and sensitivity in detecting NPAP1 in various biological samples. Validated for use in immunohistochemistry and other applications, this antibody enables accurate and reliable analysis of NPAP1 expression in tissue and cell samples.NPAP1, also known as neuronal pentraxin 1, is involved in synaptic plasticity and neuronal signaling, making it a key player in maintaining brain function and plasticity. Dysregulation of NPAP1 has been linked to neurological diseases such as Alzheimer's and Parkinson's, highlighting its importance in understanding and potentially treating these conditions.
By targeting NPAP1 with this antibody, researchers can gain insights into its role in neuronal health and disease progression, advancing our understanding of neurodegenerative disorders.Overall, the NPAP1 Antibody (PAC019223) is a valuable tool for researchers interested in unraveling the intricate mechanisms underlying neuronal function and neurodegenerative disorders. Its high specificity and reliability make it an essential component of studies aimed at elucidating the role of NPAP1 in health and disease.
Antibody Name:
NPAP1 Antibody (PACO19223)
Antibody SKU:
PACO19223
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human NPAP1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19223(NPAP1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene is located in the Prader-Willi syndrome region on chromosome 15. This gene is biallelically expressed in adult testis and brain but is paternally imprinted in fetal brain. Defects in this gene may be associated with Prader-Willi syndrome.
Synonyms:
nuclear pore associated protein 1
UniProt Protein Function:
NPAP1: May be involved in spermatogenesis.Protein type: Unknown functionChromosomal Location of Human Ortholog: 15q11.2Disease: Prader-willi Syndrome
UniProt Protein Details:
NCBI Summary:
This gene is located in the Prader-Willi syndrome region on chromosome 15. This gene is biallelically expressed in adult testis and brain but is paternally imprinted in fetal brain. Defects in this gene may be associated with Prader-Willi syndrome. [provided by RefSeq, Aug 2012]
