The NOXO1 Polyclonal Antibody (CAB10477) is a vital tool for researchers studying NOXO1, a key regulator of reactive oxygen species (ROS) production in cells. This antibody is produced in rabbits and is highly specific for detecting NOXO1 protein in human samples. Validated for use in Western blot applications, this antibody enables precise detection and analysis of NOXO1 in a variety of cell types, making it an invaluable resource for studies in oxidative stress, inflammation, and cancer research.NOXO1, a subunit of the NADPH oxidase complex, plays a crucial role in ROS generation, which is essential for immune responses and signaling pathways.
Dysregulation of NOXO1 is implicated in various pathological conditions, including cardiovascular diseases, neurodegenerative disorders, and inflammatory diseases. By studying NOXO1 function using this antibody, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
NOXO1 Rabbit Polyclonal Antibody
SKU:
CAB10477
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-370 of human NOXO1 (NP_653204.1).
This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
124056
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NOXO1 antibody (CAB10477) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
