NOX2/gp91phox Rabbit Monoclonal Antibody (CAB19701)
- SKU:
- CAB19701
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NOX2/gp91phox Rabbit Monoclonal Antibody |
SKU: | CAB19701 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NOX2/gp91phox (P04839). |
Sequence: | FHKM VAWM IALH SAIH TIAH LFNV EWCV NARV NNSD PYSV ALSE LGDR QNES YLNF ARKR IKNP EGGL YLAV TLLA GITG VVIT LCLI LIIT SSTK TIRR S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CGD; CGDX; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX; NOX2/gp91phox |
Positive Sample: | Mouse spleen,Mouse heart,Rat lung,Rat spleen,HepG2,Raji,HL-60,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 65kDa |
Observed MW: | 65kDa |
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Purification Method: | Affinity purification |
Gene ID: | 1536 |
Clone Number: | ARC0181 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |