NOSTRIN Rabbit Polyclonal Antibody (CAB15938)
- SKU:
- CAB15938
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NOSTRIN Rabbit Polyclonal Antibody |
SKU: | CAB15938 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-430 of human NOSTRIN (NP_001034813.2). |
Sequence: | ILST ENKS EFLL TDYF EEDP NSAM DKER RKSL LKPK LLRL QRDI EKAS KDKE GLER MLKT YSST SSFS DAKS QKDT AALM DENN LKLD LLEA NSYK LSSM LAEL EQRP QPSH PCSN SIFR WREK EHTH SYVK ISRP FLMK RLEN IVSK ASSG GQSN PGSS T |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | DaIP2; NOSTRIN |
Positive Sample: | HT-29,Mouse brain,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Peripheral membrane protein, cytoskeleton. |
Calculated MW: | 58kDa |
Observed MW: | 55kDa |
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
Purification Method: | Affinity purification |
Gene ID: | 115677 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |