NOX regulation-related protein 1 (NOStR1) Polyclonal Antibody (CAB15938) is a valuable tool for researchers studying the role of NOStR1, a protein involved in regulating NOX enzymes and ROS production. This polyclonal antibody, generated in rabbits, is specifically designed for detection and analysis of NOStR1 in human samples, making it ideal for studies in oxidative stress, inflammation, and cardiovascular disease.NOStR1, also known as NOSTRIN (Nitric Oxide Synthase Traffic Inducer), plays a crucial role in NOX enzyme regulation and ROS signaling pathways, which are important in various physiological and pathological processes. By targeting NOStR1, researchers can explore its function in oxidative stress responses, cellular signaling, and disease progression, providing insights into potential therapeutic targets for conditions associated with ROS dysregulation.
The NOStR1 Polyclonal Antibody (CAB15938) offers high specificity and sensitivity in Western blot applications, enabling precise detection and quantification of NOStR1 protein levels in different cell types and tissue samples. Its versatility and reliability make it a valuable tool for advancing research in the fields of redox biology, vascular health, and neurodegenerative disorders. Uncover the role of NOStR1 in cellular oxidative processes and its potential implications in disease pathogenesis with this essential research reagent.
Product Name:
NOSTRIN Rabbit Polyclonal Antibody
SKU:
CAB15938
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-430 of human NOSTRIN (NP_001034813.2).
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
Purification Method:
Affinity purification
Gene ID:
115677
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NOSTRIN Rabbit pAb (CAB15938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
