The NOS2 Polyclonal Antibody (CAB0312) is a valuable tool for researchers studying NOS2, a critical enzyme involved in immune responses and inflammation. This antibody, produced in rabbits, specifically targets human NOS2 and has been validated for use in Western blot applications. By binding to the NOS2 protein, this antibody allows for the detection and analysis of NOS2 in various cell types, making it ideal for studies in immunology, infectious diseases, and inflammatory conditions.NOS2, also known as inducible nitric oxide synthase, plays a key role in the production of nitric oxide, a signaling molecule involved in immune defense and inflammation.
Dysfunction of NOS2 has been implicated in various diseases, including septic shock, autoimmune disorders, and cardiovascular diseases. Research on NOS2 can provide insights into the mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting NOS2 activity.The NOS2 Polyclonal Antibody (CAB0312) offers researchers a reliable tool for studying NOS2 expression and activity in a wide range of experimental settings. Its high specificity and sensitivity make it an essential reagent for those seeking to better understand the role of NOS2 in health and disease.
Product Name:
iNOS Rabbit Polyclonal Antibody
SKU:
CAB0312
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 974-1143 of human iNOS (NP_000616.3).
cortical cytoskeleton, cytoplasm, cytosol, nucleoplasm, nucleus, perinuclear region of cytoplasm, peroxisomal matrix, peroxisome, plasma membrane
Calculated MW:
131kDa
Observed MW:
Refer to figures
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
4843
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of PC-12 cells using iNOS Rabbit pAb (CAB0312) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
