The NOP58 Polyclonal Antibody (CAB4749) is a high-quality antibody designed for research involving NOP58, a protein involved in ribosome biogenesis and RNA processing. This antibody is produced using rabbits, ensuring high reactivity and specificity for human samples. NOP58 is a key player in the biogenesis of ribosomes, the molecular machines responsible for protein synthesis in cells. It is essential for the maturation of ribosomal RNA and plays a crucial role in maintaining ribosome function. Dysregulation of NOP58 has been implicated in various diseases, including cancer and genetic disorders.This antibody is validated for use in Western blot applications, allowing for the detection and analysis of NOP58 in a variety of cell types.
Its high specificity and sensitivity make it an ideal tool for researchers studying ribosome biogenesis, RNA processing, and related pathways.By using the NOP58 Polyclonal Antibody in their research, scientists can gain valuable insights into the molecular mechanisms underlying ribosome biogenesis and its implications for various diseases. Its versatility and reliability make it a valuable asset for those investigating the role of NOP58 in health and disease.
Product Name:
NOP58 Rabbit Polyclonal Antibody
SKU:
CAB4749
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-529 of human NOP58 (NP_057018.1).
The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs.
Purification Method:
Affinity purification
Gene ID:
51602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NOP58 antibody (CAB4749) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
