The NOP58 Polyclonal Antibody (CAB14129) is a valuable tool for research involving the NOP58 protein, a critical component of the small nucleolar ribonucleoprotein complex involved in ribosomal RNA processing and modification. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications including Western blot and immunohistochemistry.NOP58 plays an essential role in the biogenesis of ribosomes, contributing to the proper functioning of protein synthesis machinery within cells.
Dysregulation of NOP58 has been linked to various diseases, including cancer and developmental disorders, making it a promising target for further study. By using the NOP58 Polyclonal Antibody, researchers can investigate the expression and localization of NOP58 in different cell types and tissues, shedding light on its role in cellular processes and disease pathology.
Product Name:
NOP58 Rabbit Polyclonal Antibody
SKU:
CAB14129
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-529 of human NOP58 (NP_057018.1).
The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs.
Purification Method:
Affinity purification
Gene ID:
51602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NOP58 antibody (CAB14129) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
