NOP10 Rabbit Polyclonal Antibody (CAB18250)
- SKU:
- CAB18250
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NOP10 Rabbit Polyclonal Antibody |
SKU: | CAB18250 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-64 of human NOP10 (NP_061118.1). |
Sequence: | MFLQ YYLN EQGD RVYT LKKF DPMG QQTC SAHP ARFS PDDK YSRH RITI KKRF KVLM TQQP RPVL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DKCB1; NOLA3; NOP10P; NOP10 |
Positive Sample: | HeLa,293T,BxPC-3,Mouse liver,Mouse thymus |
Cellular Localization: | box H/ACA scaRNP complex, box H/ACA snoRNP complex, nuclear body, nucleoplasm |
Calculated MW: | 8kDa |
Observed MW: | 11kDa |
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p.
Purification Method: | Affinity purification |
Gene ID: | 55505 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |