The Nono Polyclonal Antibody (CAB5282) is a key tool for researchers studying the Nono protein, a crucial component involved in multiple cellular functions. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Nono protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential resource for studies in molecular biology, cell biology, and genetics.The Nono protein, also known as non-POU domain-containing octamer-binding protein, plays a critical role in RNA processing, DNA repair, and gene expression regulation.
Its diverse functions make it a valuable target for research into various diseases, including neurological disorders, cancer, and developmental abnormalities. Understanding the mechanisms and interactions of the Nono protein is essential for unraveling its biological significance and potential therapeutic applications in these pathological conditions.
Product Name:
NONO/p54nrb Rabbit Polyclonal Antibody
SKU:
CAB5282
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NONO/p54nrb (NP_001138881.1).
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
Purification Method:
Affinity purification
Gene ID:
4841
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NONO/p54nrb Rabbit pAb (CAB5282) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
