The Nono/P54nrb Rabbit Monoclonal Antibody (CAB3800) is a highly specific antibody designed for research involving the Nono/P54nrb protein, a key player in RNA processing and DNA repair mechanisms. This antibody, raised in rabbits, is validated for use in various applications including Western blotting and immunofluorescence, enabling precise detection and analysis of Nono/P54nrb expression in different cell types.Nono/P54nrb is a multifunctional protein that plays essential roles in RNA splicing, transcriptional regulation, and DNA repair processes. Its involvement in these critical cellular functions makes it a valuable target for studies in molecular biology, cancer biology, and genetic disorders.
Understanding the regulatory mechanisms and interactions of Nono/P54nrb can provide insights into disease mechanisms and potential therapeutic strategies.Overall, the Nono/P54nrb Rabbit Monoclonal Antibody (CAB3800) offers researchers a powerful tool for investigating the function and localization of Nono/P54nrb protein in various biological contexts, making it an indispensable asset for studies in genetics, oncology, and molecular biology.
Product Name:
NONO/p54nrb Rabbit Monoclonal Antibody
SKU:
CAB3800
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 372-471 of human NONO/p54nrb (Q15233).
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
Purification Method:
Affinity purification
Gene ID:
4841
Clone Number:
ARC0836
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NONO/p54nrb Rabbit mAb (CAB3800) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
