The Nomo2 Polyclonal Antibody (CAB16614) is a crucial tool for research involving Nomo2, a protein with implications in cancer progression and metastasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to Nomo2, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for studies in oncology and tumor biology.
Nomo2, also known as a potential oncogene, plays a significant role in promoting cancer cell proliferation and migration. Its involvement in tumor development and progression makes it a promising target for research in areas such as cancer biology and therapeutic development. Exploring the functions and mechanisms of Nomo2 is essential for gaining insights into cancer biology and identifying potential targets for anti-cancer therapies.
Product Name:
NOMO2 Rabbit Polyclonal Antibody
SKU:
CAB16614
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 873-1222 of human NOMO2 (NP_001004060.1).
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
283820
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from BxPC3 cells, using NOMO2 Rabbit pAb (CAB16614) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
