NOL6 Rabbit Polyclonal Antibody (CAB14420)
- SKU:
- CAB14420
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NOL6 Rabbit Polyclonal Antibody |
SKU: | CAB14420 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1032-1146 of human NOL6 (NP_075068.2). |
Sequence: | SFCR GLLS QPGP SSLM PVLG YDPP QLYL TQLR EAFG DLAL FFYD QHGG EVIG VLWK PTSF QPQP FKAS STKG RMVM SRGG ELVM VPNV EAIL EDFA VLGE GLVQ TVEA RSER WTV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NRAP; UTP22; bA311H10.1; NOL6 |
Positive Sample: | U-251MG,A-431,HeLa,SGC-7901,Mouse lung,Mouse brain,Mouse liver,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, nucleolus. |
Calculated MW: | 128kDa |
Observed MW: | 127kDa |
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 65083 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |