The NOL11 Polyclonal Antibody (CAB15419) is a valuable tool for researchers studying NOL11, a nucleolar protein involved in ribosome biogenesis and cell proliferation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.NOL11 is essential for the assembly of ribosomal RNA and is overexpressed in certain cancer types, making it a potential target for cancer therapy. By using the NOL11 Polyclonal Antibody, researchers can detect and study the expression of NOL11 in cells and tissues, gaining insights into its role in cancer development and progression.
Furthermore, understanding the function of NOL11 may lead to the development of novel therapeutics targeting ribosome biogenesis in cancer cells, offering new treatment options for patients with cancer. The NOL11 Polyclonal Antibody is a valuable tool for advancing research in oncology and cell biology.
Product Name:
NOL11 Rabbit Polyclonal Antibody
SKU:
CAB15419
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human NOL11 (NP_056277.2).
Enables RNA binding activity. Involved in maturation of SSU-rRNA and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Located in nucleolus. Part of t-UTP complex.
Purification Method:
Affinity purification
Gene ID:
25926
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NOL11 Rabbit pAb (CAB15419) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 1s.
