NODAL Rabbit Polyclonal Antibody (CAB9902)
- SKU:
- CAB9902
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NODAL Rabbit Polyclonal Antibody |
SKU: | CAB9902 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 198-347 of human NODAL (NP_060525.3). |
Sequence: | SNLS QEQR QLGG STLL WEAE SSWR AQEG QLSW EWGK RHRR HHLP DRSQ LCRK VKFQ VDFN LIGW GSWI IYPK QYNA YRCE GECP NPVG EEFH PTNH AYIQ SLLK RYQP HRVP STCC APVK TKPL SMLY VDNG RVLL DHHK DMIV EECG CL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HTX5; NODAL |
Positive Sample: | SH-SY5Y,HepG2,293T,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 40kDa |
Observed MW: | 44kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.
Purification Method: | Affinity purification |
Gene ID: | 4838 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |