The Noct Polyclonal Antibody (CAB15805) is a specialized research tool designed for studying the Noct protein, a key regulator of circadian rhythms and sleep-wake cycles. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting Noct in human samples, making it an ideal choice for Western blot assays.Noct, also known as Nocturnin, is a critical player in the molecular clock that governs daily rhythms in behavior and physiology. Its precise control over gene expression and metabolic processes make it an intriguing target for research in chronobiology, metabolism, and sleep disorders. By elucidating the functions of Noct, scientists can gain valuable insights into factors influencing sleep patterns, energy metabolism, and overall health.
With its ability to recognize and bind to Noct protein, this antibody facilitates the investigation of Noct's role in various cell types, offering a valuable tool for scientists studying circadian biology, metabolism, and related fields. By utilizing the Noct Polyclonal Antibody, researchers can delve deeper into the intricate mechanisms underlying our body's internal clock, paving the way for potential therapeutic interventions targeting circadian disruptions and sleep-related disorders.
Product Name:
NOCT Rabbit Polyclonal Antibody
SKU:
CAB15805
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human NOCT (NP_036250.2).
The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector.
Purification Method:
Affinity purification
Gene ID:
25819
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using NOCT Rabbit pAb (CAB15805) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
