The NOC3L Polyclonal Antibody (PAC022481) is a valuable tool for researchers studying NOC3L, a crucial nuclear protein involved in cell cycle regulation and DNA repair processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot experiments. By targeting the NOC3L protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.
NOC3L, also known as nucleolar complex protein 3 homolog, plays a pivotal role in maintaining genomic stability and coordinating cellular processes essential for proper cell division. Dysregulation of NOC3L has been implicated in various diseases, including cancer and genetic disorders, highlighting its importance as a potential therapeutic target. Understanding the function and regulation of NOC3L is crucial for advancing our knowledge of these conditions and developing targeted treatments.
Antibody Name:
NOC3L Antibody (PACO22481)
Antibody SKU:
PACO22481
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human NOC3L.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using NOC3L antibody.
NOC3L: May be required for adipogenesis. Belongs to the CBF/MAK21 family.Protein type: Nucleolus; RNA-bindingChromosomal Location of Human Ortholog: 10q23.33Cellular Component: nucleusMolecular Function: chromatin binding