NOB1 Rabbit Polyclonal Antibody (CAB17690)
- SKU:
- CAB17690
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NOB1 Rabbit Polyclonal Antibody |
SKU: | CAB17690 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NOB1 (NP_054781.1). |
Sequence: | MAPV EHVV ADAG AFLR HAAL QDIG KNIY TIRE VVTE IRDK ATRR RLAV LPYE LRFK EPLP EYVR LVTE FSKK TGDY PSLS ATDI QVLA LTYQ LEAE FVGV SHLK QEPQ KVKV SSSI QHPE TPLH ISGF HLPY KPKP PQET EKGH SACE PENL EFSS FMFW RNPL PNID HELQ ELLI DRGE DVPS EEEE EEEN GFED RKDD SDDD GGGW ITPS NIKQ IQQE LEQC DVPE DV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ART-4; NOB1P; MST158; MSTP158; PSMD8BP1; NOB1 |
Positive Sample: | BxPC-3,LO2,rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nucleoplasm |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).
Purification Method: | Affinity purification |
Gene ID: | 28987 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |