NOA1 Antibody (PACO52590)
- SKU:
- PACO52590
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
NOA1 Antibody (PACO52590)
The NOA1 Polyclonal Antibody (PAC052590) is an essential tool for researchers studying NOA1, a protein involved in mitochondrial ribosome biogenesis and energy metabolism. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of NOA1 in a variety of cell types.
Ideal for studies in mitochondrial biology and bioenergetics, the NOA1 Polyclonal Antibody is crucial for understanding the role of NOA1 in cellular function and its potential implications in metabolic disorders and mitochondrial dysfunction. Get reliable and accurate results with this high-quality antibody for your research needs.
| Antibody Name: | NOA1 Antibody (PACO52590) |
| Antibody SKU: | PACO52590 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:500-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Nitric oxide-associated protein 1 protein (42-174AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, Mouse kidney tissue. All lanes: NOA1 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 79 kDa. Observed band size: 79 kDa. |
 | IHC image of PACO52590 diluted at 1:500 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP. |
| Synonyms: | Nitric oxide-associated protein 1, NOA1, C4orf14 |
| UniProt Protein Function: | MGC3232: a protein of unknown function. Protein type: MitochondrialChromosomal Location of Human Ortholog: 4q12Cellular Component: mitochondrionMolecular Function: GTP binding; GTPase activity; protein bindingBiological Process: mitochondrial translation; regulation of cellular respiration; ribosome biogenesis and assembly |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a nuclear-encoded GTPase that functions in the mitochondrion. Upon translation, this protein is imported into the nucleus and then into the nucleolus before being exported to the mitochondrion. The encoded protein is required for oxygen-dependent regulation of mitochondrial respiratory complexes and for mitochondrial protein synthesis. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q8NC60 |
| NCBI GenInfo Identifier: | 14150078 |
| NCBI Gene ID: | 84273 |
| NCBI Accession: | NP_115689.1 |
| UniProt Secondary Accession: | Q8NC60,Q8N7L6, Q9BSQ9 |
| UniProt Related Accession: | Q8NC60 |
| Molecular Weight: | 78,458 Da |
| NCBI Full Name: | nitric oxide-associated protein 1 |
| NCBI Synonym Full Names: | nitric oxide associated 1 |
| NCBI Official Symbol: | NOA1Â Â |
| NCBI Official Synonym Symbols: | MTG3; hNOA1; C4orf14; hAtNOS1; mAtNOS1Â Â |
| NCBI Protein Information: | nitric oxide-associated protein 1 |
| UniProt Protein Name: | Nitric oxide-associated protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | NO-associated protein |
| UniProt Gene Name: | NOA1Â Â |
| UniProt Entry Name: |
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