The NNMT Polyclonal Antibody (CAB6673) is a valuable tool for researchers studying nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation of nicotinamide and various xenobiotics. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.NNMT is known to be upregulated in various cancers and metabolic disorders, making it a potential target for therapeutic intervention. By using the NNMT Polyclonal Antibody, researchers can investigate the expression and activity of NNMT in different cell types and tissues, shedding light on its role in disease development and progression.
Furthermore, understanding the regulation of NNMT may offer insights into novel treatment strategies for conditions linked to its dysregulation. Whether studying cancer biology, metabolism, or drug metabolism, the NNMT Polyclonal Antibody is a valuable resource for researchers looking to advance their understanding of NNMT function and its implications in human health and disease.
Product Name:
NNMT Rabbit Polyclonal Antibody
SKU:
CAB6673
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human NNMT (NP_006160.1).
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Purification Method:
Affinity purification
Gene ID:
4837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of A-549 cells, using NNMT antibody (CAB6673) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
