The NNMT Polyclonal Antibody (CAB14030) is a valuable tool for researchers studying Nicotinamide N-methyltransferase (NNMT), an enzyme involved in the regulation of cellular energy metabolism and the maintenance of homeostasis. The antibody, produced in rabbits, is highly specific for detecting NNMT in human samples and has been validated for use in Western blot applications.NNMT plays a crucial role in the metabolism of nicotinamide, a form of vitamin B3, and has been implicated in various diseases, including cancer, metabolic disorders, and neurological disorders.
By targeting NNMT, researchers can gain insight into its role in these diseases and potentially develop new therapeutic strategies.This polyclonal antibody enables the detection and analysis of NNMT in different cell types, making it an essential tool for studies in biochemistry, metabolism, and disease research. Understanding the functions and regulatory mechanisms of NNMT can provide valuable insights into the development of novel treatments and therapies for a range of conditions.
Product Name:
NNMT Rabbit Polyclonal Antibody
SKU:
CAB14030
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human NNMT (NP_006160.1).
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Purification Method:
Affinity purification
Gene ID:
4837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NNMT antibody (CAB14030) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
