The NNMT Monoclonal Antibody is a vital tool for researchers studying nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation of nicotinamide and other pyridines. This antibody, generated using hybridoma technology, is highly specific to NNMT and suitable for various applications including immunofluorescence, immunohistochemistry, and Western blot.NNMT plays a key role in the regulation of cellular energy metabolism, lipid metabolism, and inflammation, making it a potential target for therapeutic interventions in metabolic disorders, cancer, and neurodegenerative diseases.
The NNMT Monoclonal Antibody enables accurate detection and analysis of NNMT expression in different tissues and cell types, providing valuable insights into its function and potential implications for disease pathology.Researchers in the fields of metabolism, oncology, and neuroscience can benefit from the use of the NNMT Monoclonal Antibody to advance their understanding of NNMT-related pathways and mechanisms. By unlocking the secrets of NNMT, scientists may uncover novel therapeutic strategies for addressing a range of human health conditions.
Product Name:
NNMT Monoclonal Antibody
SKU:
CAB23786
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant protein of human NNMT.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:5000
Synonyms:
NNMT; nicotinamide N-methyltransferase
Positive Sample:
Hela
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
29kDa
Observed MW:
28kDa
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Purification Method:
Affinity purification
Gene ID:
4837
Clone Number:
ARC61849
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of Hela, using NNMT Rabbit mAb (CAB23786) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
