The NMT2 Polyclonal Antibody (CAB7042) is a valuable tool for researchers studying N-myristoyltransferase 2 (NMT2), an essential enzyme involved in protein myristoylation, a process critical for protein-protein interactions and subcellular localization. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human NMT2 protein, making it an ideal choice for Western blot analysis.NMT2 has been implicated in various cellular processes, including cell cycle regulation, apoptosis, and signal transduction pathways.
Dysregulation of NMT2 has been linked to diseases such as cancer, neurological disorders, and viral infections, highlighting the importance of studying this enzyme. By using the NMT2 Polyclonal Antibody, researchers can gain insights into the function and regulation of NMT2 in normal cellular physiology and disease states, paving the way for the development of targeted therapies.
Product Name:
NMT2 Rabbit Polyclonal Antibody
SKU:
CAB7042
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human NMT2 (NP_004799.1).
This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl group to the N-terminal glycine residue of many signaling proteins, including the human immunodeficiency virus type 1 (HIV-1) proteins, Gag and Nef. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9397
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NMT2 antibody (CAB7042) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
