The NMNAT2 Polyclonal Antibody (CAB13833) is a valuable tool for researchers studying NMNAT2, an enzyme involved in the biosynthesis of NAD+ and neuroprotection. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for a variety of research applications, including Western blot analysis. By binding to NMNAT2, this antibody allows for the detection and analysis of this enzyme in different cell types.NMNAT2 is known for its role in cellular metabolism and its potential neuroprotective effects, making it a key target for studies in neurodegenerative diseases and aging.
Research on NMNAT2 may provide insights into the mechanisms of neuronal health and survival, as well as potential therapeutic interventions for conditions such as Alzheimer's disease and Parkinson's disease.Overall, the NMNAT2 Polyclonal Antibody is a valuable tool for researchers interested in exploring the functions and implications of NMNAT2 in various biological processes, offering insights that may contribute to the development of new treatments for neurodegenerative disorders.
Product Name:
NMNAT2 Rabbit Polyclonal Antibody
SKU:
CAB13833
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human NMNAT2 (NP_733820.1).
This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23057
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NMNAT2 antibody (CAB13833) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
