The NME8 Polyclonal Antibody (CAB17153) is a versatile tool for researchers studying NME8, a protein associated with cell proliferation and cancer development. This rabbit-raised antibody is highly specific to human samples and is validated for Western blot applications, allowing for accurate detection and analysis of NME8 in various cell types.NME8, also known as Nucleoside Diphosphate Kinase 8, plays a crucial role in regulating nucleotide metabolism and cell growth. Dysregulation of NME8 has been linked to tumorigenesis and metastasis in various cancer types, making it a promising target for cancer research.
By using the NME8 Polyclonal Antibody, researchers can gain valuable insights into the function and expression of NME8 in both normal and diseased cells.With its high reactivity and specificity, the NME8 Polyclonal Antibody is an essential tool for studies exploring the role of NME8 in cancer biology and cell proliferation. By better understanding the mechanisms involving NME8, researchers can potentially uncover novel therapeutic targets for treating cancer and other diseases related to abnormal cell growth.
Product Name:
NME8 Rabbit Polyclonal Antibody
SKU:
CAB17153
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 299-588 of human NME8 (NP_057700.3).
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
Purification Method:
Affinity purification
Gene ID:
51314
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NME8 Rabbit pAb (CAB17153) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
