The NME7 Polyclonal Antibody (CAB14882) is a valuable tool for research involving NME7, a protein involved in nucleoside diphosphate kinase activity. This antibody is produced in rabbits and is highly reactive with human samples, making it an ideal choice for researchers studying NME7 in various cell types. NME7 is an important enzyme that catalyzes the transfer of gamma-phosphate from nucleoside triphosphates to nucleoside diphosphates, playing a crucial role in cellular energy metabolism and nucleotide biosynthesis. Dysregulation of NME7 has been linked to various diseases, including cancer and neurodevelopmental disorders, highlighting its significance in cellular processes.
With its specificity and sensitivity in detecting NME7, this antibody is validated for use in Western blot applications, enabling researchers to accurately detect and analyze the protein in their experiments. By understanding the function and regulation of NME7, researchers can gain insights into its role in disease pathogenesis and potentially identify novel therapeutic targets for various conditions.
Product Name:
NME7 Rabbit Polyclonal Antibody
SKU:
CAB14882
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-376 of human NME7 (NP_037462.1).
This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29922
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NME7 Rabbit pAb (CAB14882) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
