The NME4 Polyclonal Antibody (CAB8350) is a valuable tool for researchers studying NME4, a protein involved in nucleoside diphosphate kinase-mediated tumor cell invasion. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for various applications such as Western blotting.NME4, also known as non-metastatic cells 4 protein, plays a crucial role in regulating tumor cell migration and invasion, making it a promising target for cancer research. By binding specifically to NME4, this antibody enables the detection and analysis of the protein in different cell types, facilitating studies focused on understanding the molecular mechanisms underlying tumor progression.
The NME4 Polyclonal Antibody is a valuable tool for researchers aiming to unravel the role of NME4 in cancer metastasis and develop targeted therapies that inhibit tumor invasion and metastasis. With its high specificity and validated performance in Western blot applications, this antibody is a reliable option for investigating the function and therapeutic potential of NME4 in cancer biology.
Product Name:
NME4 Rabbit Polyclonal Antibody
SKU:
CAB8350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human NME4 (NP_005000.1).
The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 [PubMed 9099850]).
Purification Method:
Affinity purification
Gene ID:
4833
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NME4 antibody (CAB8350) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
