The NME2 Rabbit Monoclonal Antibody (CAB5621) is a powerful tool for studying NME2, a key protein involved in cellular processes such as DNA replication and repair, as well as cell migration and invasion. This antibody is specifically designed for use in research applications, particularly in immunohistochemistry (IHC) and immunofluorescence (IF) studies. Raised in rabbits, this monoclonal antibody shows high specificity and sensitivity for detecting NME2 in various cell types and tissues, making it an ideal choice for researchers studying cancer biology, metastasis, and tumor progression. By targeting NME2, researchers can gain valuable insights into the mechanisms underlying these processes and potentially identify new therapeutic targets for cancer treatment.
Additionally, the validation of this antibody for use in Western blot applications further enhances its versatility for studying NME2 protein levels in different experimental settings. Its high reactivity with human samples provides researchers with a reliable tool for investigating the role of NME2 in human health and disease.Overall, the NME2 Rabbit Monoclonal Antibody (CAB5621) offers researchers a reliable and specific tool for studying the function and expression of NME2 in various biological contexts, with the potential to contribute to a better understanding of cancer biology and the development of novel therapeutic strategies.
Product Name:
NME2/NM23B Rabbit Monoclonal Antibody
SKU:
CAB5621
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-152 of human NME2/NM23B (P22392).
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.
Purification Method:
Affinity purification
Gene ID:
4831
Clone Number:
ARC1412
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various lysates, using NME2/NM23B Rabbit mAb (CAB5621) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.