NMDAR2A Rabbit Monoclonal Antibody (CAB19089)
- SKU:
- CAB19089
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | NMDAR2A Rabbit Monoclonal Antibody |
SKU: | CAB19089 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human NMDAR2A (Q12879). |
Sequence: | RELD LSRP SRSI SLKD RERL LEGN FYGS LFSV PSSK LSGK KSSL FPQG LEDS KRSK SLLP DHTS DNPF LHSH RDDQ RLVI GRCP SDPY KHSL PSQA VNDS Y |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LKS; EPND; FESD; NR2A; GluN2A; NMDAR2A |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 165kDa |
Observed MW: | 180kDa |
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2903 |
Clone Number: | ARC0410 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |