nm23 Polyclonal Antibody (CAB24540)
- SKU:
- CAB24540
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Description
Product Name: | nm23 Polyclonal Antibody |
SKU: | CAB24540 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human nm23 (NP_000260.1/NP_002503.1). |
Sequence: | MANC ERTF IAIK PDGV QRGL VGEI IKRF EQKG FRLV GLKF MQAS EDLL KEHY VDLK DRPF FAGL VKYM HSGP VVAM VWEG LNVV KTGR VMLG ETNP ADSK PGTI RGDF CIQV GRNI IHGS DSVE SAEK EIGL WFHP EELV DYTS CAQN WIYE |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; PUF; NDKB; NDPKB; NM23B; NDPK-B; NM23-H2; nm23 |
Conjugate: | Unconjugated |
Calculated MW: | 17kDa |
Observed MW: | Refer to figures |
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.
Purification Method: | Affinity purification |
Gene ID: | 4830/4831 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |