The NLRX1 Polyclonal Antibody (CAB4976) is a valuable tool for researchers studying NLRX1, a key regulator of innate immune responses. This antibody, generated in rabbits, has been rigorously tested for specificity and sensitivity in Western blot analysis, ensuring reliable and reproducible results. By targeting the NLRX1 protein, this antibody allows for the investigation of NLRX1 expression and function in various experimental settings.NLRX1 is a mitochondrial protein that plays a critical role in regulating inflammation and antiviral responses. Dysregulation of NLRX1 has been implicated in the pathogenesis of infectious diseases, autoimmune disorders, and metabolic disorders.
Research on NLRX1 is essential for understanding the mechanisms underlying these diseases and developing targeted therapies to modulate NLRX1 activity.With its high specificity and sensitivity, the NLRX1 Polyclonal Antibody (CAB4976) is an invaluable tool for researchers investigating the role of NLRX1 in immunity, inflammation, and disease. Its versatility and reliability make it ideal for a wide range of studies in immunology, microbiology, and molecular biology.
Product Name:
NLRX1 Rabbit Polyclonal Antibody
SKU:
CAB4976
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 87-360 of human NLRX1 (NP_078894.2).
WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells
Synonyms:
NOD5; NOD9; NOD26; DLNB26; CLR11.3; NLRX1
Positive Sample:
Mouse heart
Conjugate:
Unconjugated
Cellular Localization:
Mitochondrion outer membrane.
Calculated MW:
108kDa
Observed MW:
108kDa
The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
79671
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart, using NLRX1 Rabbit pAb (CAB4976) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.