UniProt Protein Function: | NLRP9: Involved in inflammation (Potential). Belongs to the NLRP family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 19q13.42Cellular Component: cytoplasmMolecular Function: ATP binding |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q7RTR0 |
NCBI GenInfo Identifier: | 74762418 |
NCBI Gene ID: | 338321 |
NCBI Accession: | Q7RTR0.1 |
UniProt Secondary Accession: | Q7RTR0,Q86W27, B2RN12 |
UniProt Related Accession: | Q7RTR0 |
Molecular Weight: | 112,593 Da |
NCBI Full Name: | NACHT, LRR and PYD domains-containing protein 9 |
NCBI Synonym Full Names: | NLR family, pyrin domain containing 9 |
NCBI Official Symbol: | NLRP9Â Â |
NCBI Official Synonym Symbols: | NOD6; NALP9; PAN12; CLR19.1Â Â |
NCBI Protein Information: | NACHT, LRR and PYD domains-containing protein 9; PYRIN and NACHT-containing protein 12; NACHT, LRR and PYD containing protein 9; NACHT, leucine rich repeat and PYD containing 9; nucleotide-binding oligomerization domain protein 6; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 9 |
UniProt Protein Name: | NACHT, LRR and PYD domains-containing protein 9 |
UniProt Synonym Protein Names: | Nucleotide-binding oligomerization domain protein 6; PYRIN and NACHT-containing protein 12 |
Protein Family: | NACHT, LRR and PYD domains-containing protein |
UniProt Gene Name: | NLRP9Â Â |
UniProt Entry Name: | NALP9_HUMAN |