The NLRP6 Polyclonal Antibody is a powerful tool for researchers studying the NLRP6 protein, an essential component of the innate immune system. This antibody, generated using rabbit immunization techniques, is highly specific for human samples and has been rigorously tested in Western blot analyses. By targeting the NLRP6 protein, researchers can accurately detect and analyze its expression in various cell types, making it an invaluable asset for studies in immunology and inflammatory disease research.
NLRP6 is a key player in regulating the inflammatory response and maintaining immune homeostasis, making it a promising target for investigating conditions such as autoimmune disorders, infectious diseases, and inflammatory bowel diseases. The NLRP6 Polyclonal Antibody provides researchers with the means to delve deeper into the function of NLRP6 and its role in immune modulation, paving the way for potential therapeutic interventions and novel treatment strategies in the future.
Product Name:
Nlrp6 Polyclonal Antibody
SKU:
CAB23267
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 124-237 of mouse Nlrp6(NP_598707.2 ).
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation.
Purification Method:
Affinity purification
Gene ID:
101613
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Rat colon, using Nlrp6 Rabbit pAb (CAB23267) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
