NLRP6 Rabbit Polyclonal Antibody (CAB15628)
- SKU:
- CAB15628
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | NLRP6 Rabbit Polyclonal Antibody |
SKU: | CAB15628 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-110 of human NLRP6 (NP_612202.2). |
Sequence: | MDQP EAPC SSTG PRLA VARE LLLA ALEE LSQE QLKR FRHK LRDV GPDG RSIP WGRL ERAD AVDL AEQL AQFY GPEP ALEV ARKT LKRA DARD VAAQ LQER RLQR LGLG SG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | AVR; NAVR; PAN3; NALP6; PYPAF5; CLR11.4; NAVR/AVR; NLRP6 |
Positive Sample: | Mouse large intestine,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, inflammasome complex, NLRP6 inflammasome complex, nuclear membrane, plasma membrane |
Calculated MW: | 99kDa |
Observed MW: | 102kDa |
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 171389 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |