NLRP10 Rabbit Polyclonal Antibody (CAB15976)
- SKU:
- CAB15976
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | NLRP10 Rabbit Polyclonal Antibody |
SKU: | CAB15976 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NLRP10 (NP_789791.1). |
Sequence: | MAMA KARK PREA LLWA LSDL EEND FKKL KFYL RDMT LSEG QPPL ARGE LEGL IPVD LAEL LISK YGEK EAVK VVLK GLKV MNLL ELVD QLSH ICLH DYRE VYRE HVRC LEEW QEAG VNGR YNQV LLVA KPSS ESPE SLAC PFPE QELE SVTV EALF DSGE KPSL APSL VVLQ GSAG TGKT TLAR KMVL DWAT GTLY PGRF DYVF YVSC KEVV LLLE SKLE QLLF WCCG DNQA PVTE ILRQ PERL LFIL DGFD ELQR PFEE KLKK RGLS PKES LLHL LIRR HTLP TCSL LITT RPLA LRNL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NOD8; PAN5; PYNOD; NALP10; CLR11.1; NLRP10 |
Positive Sample: | U-87MG,LO2,HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm. |
Calculated MW: | 75kDa |
Observed MW: | 75kDa |
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
Purification Method: | Affinity purification |
Gene ID: | 338322 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |