NLRP1 Rabbit Polyclonal Antibody (CAB16212)
- SKU:
- CAB16212
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | NLRP1 Rabbit Polyclonal Antibody |
SKU: | CAB16212 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1370-1473 of human NLRP1 (NP_127497.1). |
Sequence: | PSPL DAPQ LLHF VDQY REQL IARV TSVE VVLD KLHG QVLS QEQY ERVL AENT RPSQ MRKL FSLS QSWD RKCK DGLY QALK ETHP HLIM ELWE KGSK KGLL PLSS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NAC; JRRP; MSPC; AIADK; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S; NLRP1 |
Positive Sample: | K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, inflammasome complex, NLRP1 inflammasome complex, nucleolus, nucleoplasm, nucleus |
Calculated MW: | 166kDa |
Observed MW: | 160kDa |
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 22861 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |