The NLRC5 Polyclonal Antibody (CAB16740) is a crucial tool for researchers studying the NLRC5 protein, a key player in immune regulation and inflammation pathways. This antibody, generated in rabbits, has high specificity and sensitivity for detecting NLRC5 in human samples, making it ideal for Western blot applications. NLRC5, also known as NOD-like receptor C5, is known to function as a transcriptional regulator that plays a critical role in immune responses and inflammatory processes.
Understanding the function and regulation of NLRC5 is essential for unraveling its role in various diseases, including cancer, autoimmune disorders, and infectious diseases. This polyclonal antibody targets NLRC5, allowing for accurate detection and analysis in a variety of cell types. Its versatility and reliability make it a valuable tool for researchers in immunology and cancer research seeking to explore the intricate mechanisms of immune regulation and inflammatory responses.
Product Name:
NLRC5 Rabbit Polyclonal Antibody
SKU:
CAB16740
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant protein of human NLRC5
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
NOD4; NOD27; CLR16.1; NLRC5
Positive Sample:
mouse lung
Cellular Localization:
centrosome, cytoplasm, cytosol, nucleus
Calculated MW:
205kDa
Observed MW:
204kDa
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
Purification Method:
Affinity purification
Gene ID:
84166
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse lung, using NLRC5 antibody (CAB16740) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
