The NLRC4 Polyclonal Antibody is a valuable tool for researchers studying NLRC4, a key player in the innate immune system. This antibody, produced in rabbits, has been shown to have high reactivity with human samples and is suitable for Western blot applications. By binding specifically to the NLRC4 protein, this antibody allows for the detection and analysis of NLRC4 in various cell types, making it ideal for studies in immunology and infectious disease research.NLRC4, also known as Nod-like receptor C4, is an important regulator of inflammation and plays a crucial role in the response to bacterial and viral infections.
Dysregulation of NLRC4 has been linked to various inflammatory disorders, making it a promising target for therapeutic intervention. Research on NLRC4 is essential for developing treatments for infectious diseases and inflammatory conditions, as well as gaining a deeper understanding of the innate immune response.
Product Name:
NLRC4 Polyclonal Antibody
SKU:
CAB24336
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 71-170 of mouse NLRC4. (NP_001028539.1).
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
268973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse large intestine, using NLRC4 Rabbit pAb (CAB24336) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
