The NLN Polyclonal Antibody (CAB13112) is a valuable tool for researchers studying NLN, a key protein involved in various cellular processes including gene regulation, DNA repair, and cell cycle progression. This antibody, produced in rabbits, is highly specific for NLN and is suitable for use in Western blotting and immunohistochemistry applications.NLN, also known as neurolysin, is a zinc-dependent metallopeptidase that plays a crucial role in maintaining cellular homeostasis and proper functioning of the nervous system. Dysregulation of NLN has been linked to neurodegenerative disorders, cancer, and other diseases, highlighting its importance as a potential therapeutic target.
By using the NLN Polyclonal Antibody, researchers can accurately detect and analyze NLN expression in different cell types and tissues, providing valuable insights into its physiological functions and potential therapeutic implications. This antibody is essential for advancing our understanding of NLN's role in health and disease, paving the way for new treatment strategies and drug development.
Product Name:
NLN Rabbit Polyclonal Antibody
SKU:
CAB13112
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 630-704 of human NLN (NP_065777.1).
This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
Purification Method:
Affinity purification
Gene ID:
57486
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of HeLa, using NLN Rabbit pAb (CAB13112) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
